Briscoe earned his third win this season and second of the playoffs to join teammate Denny Hamlin in becoming eligible for the title in the Nov. 2 season finale at Phoenix Raceway.
After winning just twice in his first 160 Cup starts, Briscoe has won three of the last 18 races with victories at Pocono Raceway, Darlington Raceway and Talladega.
FURTHER: Click here to see results from Talladega Superspeedway I Click here to view the cumulative report I Click here to view the sanctions report I Click here to view race notes.
He became the 11th different winner in the last 11 races at Talladega, extending a record at the 2.66-mile oval. It’s also the first superspeedway win for Briscoe, who clinched a title berth after entering Talladega 15 points above the cut line.
Despite being penalized for speeding in the pits, Briscoe recovered to lead seven times over 16 laps, winning on a pass from Bubba Wallace on the final lap to take the lead.
It is the first superspeedway victory for the Joe Gibbs Racing driver.
Hamlin and Briscoe have secured two of the four title-eligible spots for the Nov. 2 season finale at Phoenix Raceway, where the top finisher of the remaining playoff drivers will win the championship.
The final two spots in the Championship 4 field will be settled in the Oct. 26 race at Martinsville Speedway with at least one determined by points standings.
Heading into the Round of 16 final, Christopher Bell (37 points above the cut line) and Kyle Larson (plus-35) are above the cut line. William Byron (minus-36), Joey Logano (minus-38), Ryan Blaney (minus-47) and Chase Elliott (minus-62) are below the cut line.
The Joe Gibbs Racing driver joins teammate Denny Hamlin in the title race.
Logano, Blaney and Elliott have wins at Martinsville
Here is the order of finish at Talladega Superspeedway
1. Chase Briscoe, #19 Toyota
2. Todd Gilliland, #34 Ford
3. Ty Gibbs, #54 Toyota
4. Bubba Wallace, #23 Toyota
5. Cole Custer, #41 Ford
6. Carson Hocevar, #77 Chevrolet
7. Tyler Reddick, #45 Toyota
8. Christopher Bell, Toyota number 20
9. Zane Smith, #38 Ford
10. Brad Keselowski, #6 Ford
11. Shane Van Gisbergen, #88 Chevrolet
12. Daniel Suárez, Chevrolet No. 99
13. Ross Chastain, #1 Chevrolet
14. John Hunter Nemechek, #42 Toyota
15. Ryan Preece, #60 Ford
16. Joey Logano, Ford number 22
17. Michael McDowell, #71 Chevrolet
18. Casey Mears, #66 Ford
19. Kyle Busch, No. 8 Chevrolet
20. Ty Dillon, #10 Chevrolet
21. Anthony Alfredo, Chevrolet No. 62
22. Austin Hill, #33 Chevrolet
23. Ryan Blaney, #12 Ford
24. Denny Hamlin, #11 Toyota
25. William Byron, #24 Chevrolet
26. Kyle Larson, #5 Chevrolet
27. Austin Dillon, #3 Chevrolet
28. BJ McLeod, #78 Ford
29. Alex Bowman, #48 Chevrolet
30. Chris Buescher, #17 Ford
31. Cody Ware, #51 Ford
32. Riley Herbst, #35 Toyota
33. Josh Berry, #21 Ford
34. Austin Cindric, #2 Ford
35. Erik Jones, #43 Toyota
36. Noah Gragson, Ford #4
37. AJ Allmendinger, #16 Chevrolet
38. Ricky Stenhouse Jr., #47 Chevrolet
39. Justin Haley, #7 Chevrolet
40. Chase Elliott, #9 Chevrolet