Top Analyst Drops Stunning Price Target on Eli Lilly Stock

Top Analyst Drops Stunning Price Target on Eli Lilly Stock
Top Analyst Drops Stunning Price Target on Eli Lilly Stock

Bernstein just added new fuel to Eli Lilly’s (LLY) endless rally, as the company raised its stock price target to $1,300 from $1,100.

For perspective, this is an 18% increase compared to the previous target, although it represents a 21% to 22% advantage compared to Lilly’s current stock price.

Analyst Courtney Breen believes Wall Street is still not taking into account how massive the company’s next wave of GLP-1 catalysts could be.

She feels that Lilly’s incredible leap into the trillion-dollar club, as reported by Reuters, was not the best, and that 2026 could be the turning point where its illustrious history transitions into genuine “churn and rise” momentum.

Additionally, with the imminent launch of orforglipron, White House policy is moving toward broader coverage, while tirzepatide has evolved into a multi-indication platform.

Breen therefore sees a setup that offers many advantages.

Furthermore, it is important to note that according to Tipranks, Breen wears a standout 94% success rateand 32 of his 34 stock options turned a profit.

In addition to that, their recommendations offer solid +21.5% average return per qualificationpositioning her among Wall Street’s top analysts.

<em>Bernstein’s Courtney Breen significantly raised Eli Lilly’s price target, citing more potent GLP-1 catalysts ahead</em>.Photo by NurPhoto on Getty Images” loading=”eager” height=”627″ width=”960″ class=”yf-1gfnohs loader”/></div>
</div><figcaption class=Bernstein’s Courtney Breen significantly raised Eli Lilly’s price target, citing stronger GLP-1 catalysts ahead.Photo by NurPhoto on Getty Images

Bernstein analyst Breen’s optimism about Eli Lilly is largely based on what she calls an “incredibly rich” catalyst path spanning more than two years.

Most of it is due to how much earnings power Mr. Market hasn’t modeled into the stock.

At the center is Lilly’s oral GLP-1. orforglipronwhich Breen believes will drive the company’s next stage of expansion.

More Medicare/Medicaid

This is partly due to a favorable political context in the United States that has changed President Donald Trump’s GLP-1 agreement, along with growing global reimbursement channels.

Breen and his team developed a financial model that breaks down Medicare, Medicaid, commercial and cash demand into a quarterly schedule that spans 2027 and annually to 2030.

The results showed that the consensus was still too conservative regarding volumes and potential sales.

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The breakthrough is expected to occur in 2026.

This is when orforglipron goes from being a promise to becoming a profit driver, with estimated sales at an excellent level. 1.8 billion dollarswhich is more than 3 times the street view of $550 million.

What is even more impressive is that Breen emphasizes that these high figures are US-only assumptions based on almost 80,000 scripts per week in the oral obesity market.

Weight loss drugs have effectively been the new fuel for the stock market lately, and it looks like the trajectory isn’t slowing down anytime soon.

The science behind the rise of GLP-1 (i.e. weight loss drugs) is simple.

These drugs basically turn down the volume when you’re hungry while adding speed punches in the stomach.

These medications mimic gut hormones released after eating, signaling to our brain that we are full much faster, while slowing gastric emptying and improving insulin release in the process.

The result is fewer cravings and consistent weight loss over time.

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Furthermore, estimates suggest that we are just beginning this growth journey.

For example, Morgan Stanley estimates that brand-name obesity drugs generated a huge 6 billion dollars in 2023 and almost 15 billion dollars in 2024according to Morgan Stanley. Furthermore, he predicts that the global market will reach 105 billion dollars by 2030 and possibly $150 billion It will peak around 2035.

Similarly, JPMorgan sees GLP-1 for diabetes and obesity collectively contributing $100 billion by 2030.

  • Injectables
    Eli Lilly: Mounjaro (tirzepatide) for type 2 diabetes and Zepbound for obesity and obstructive sleep apnea (OSA). Novo Nordisk – Ozempic (semaglutide) for diabetes and Wegovy for obesity; helped boost Novo’s obesity care sales to 65.1 billion Danish crowns ($9.5 billion) in 2024.

  • Pills (on the market or in advanced stage)
    Novo Nordisk – oral semaglutide (Rybelsus/high dose 50 mg): In the OASIS-1 trial, 50 mg oral semaglutide once daily resulted in an average weight loss of almost 15% (17% in adherent patients). Eli Lilly – orforglipron: a small molecule GLP-1 pill taken once a day; Phase 3 data show an average weight loss of about 9 to 10 percent over 72 weeks, versus 2 to 3 percent with placebo.

Lilly worked its way into the billion-dollar club, accomplishing the feat on November 21, led by its robust GLP-1 engine.

The company’s weight loss push has effectively become a bona fide metabolic health franchise, led by dominance of tirzepatide, along with a series of clinical victories.

The numbers explain why investors embraced its story, with skyrocketing sales, tech-style margins and a pipeline that continues to grow its addressable market.

Now, with an oral GLP-1 in motion, the flywheel that just propelled Lilly to $1 billion continues to accelerate.

  • Record sales of LPG-1: In Q3 2025, BioPharma Dive Reported Product Release of Tirzepatide $10 billion+including $6.5 billion from Mounjaro (+109% year over year) and $3.6 billion from Zepbound (+185% year-on-year), increasing total sales 54% year over year to $17.6 billion.

  • An oil pipeline that continued to expand the market:According to JAMA Network, Zepbound’s OSA approval (sleep apnea) formed a new reimbursable category, while tapping into an estimated population close to billion people globally.

  • Technological style profitability: EPS hit $7.02the margins moved towards the mid 80’swhile its valuation jumped almost 200% in the last three years.

  • Next Generation Expansion: Orforglipron’s strong Phase 3 data positions Lilly to dominate both injectable and oral GLP-1 markets by 2030.

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This story was originally published by TheStreet on November 25, 2025, where it first appeared in the Investments section. Add TheStreet as a preferred source by clicking here.

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